The best model to understand the physiology and functionality of the PM is the three-pore model proposed by Rippe. Today, it is evident that the physiology of the peritoneal membrane (PM) is more complex than it was previously thought to be, and that it is not just a membrane that answers passively to diffusion and convection. In the last decade, PD research has concentrated on trying to improve the quality of the technique and to diminish its complications. Peritoneal dialysis (PD) is an alternative to haemodialysis for the treatment of end-stage renal disease. ![]() ![]() Bicarbonate/lactate buffered solution, biocompatibility, epithelial-to-mesenchymal transition, mesothelial cells, peritoneal dialysis, peritoneal transport rate INTRODUCTION
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